Clinical Studies

OUR SCIENCE — CLINICAL STUDIES

Backed by science.

We build products that we would take ourselves. In an industry overrun with claims, labels, and hard-to-read ingredients, we're here to clarify the unknown: Weider products are backed by published clinical studies. Every study below is the full paper — read it yourself.

THE EVIDENCE, BY PRODUCT

Eight formulas. Fifty + studies.

HEART HEALTH

Artery Health

HEART HEALTH

Red Yeast Rice

MEN'S HEALTH

Weider Prime

SLEEP & STRESS

Sleep — Melatonin Free

MEN'S HEALTH

Prostate Health

LIVER & KIDNEY

Liver & Kidney

WOMEN'S HEALTH

Hormone Balance

LONGEVITY

Beyond NAD+

CLINICAL STUDIES · HEART HEALTH

Artery Health

Three key ingredients: Vitamin K2 as menaquinone-7, aronia berry, and ginger. Menaquinone-7 helps the body transport calcium effectively — the only clinically supported, patented vitamin K2 on the market today.

4 published studies

The most important human clinical trials on Vitamin K2

NattoPharma

Backed by science.

Eight formulas. Fifty + studies.

Artery Health

The most important human clinical trials on Vitamin K2

Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women

Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status

Effect of vitamin K2 on progression of atherosclerosis and vascular calcification

Red Yeast Rice

The activity and absorption relationship of cholesterol and phytosterols | NattoPharma

Phytosterols supplementation decreases plasma small and dense LDL levels in metabolic syndrome patients on a westernized-type diet | Nutrition, Metabolism & Cardiovascular Diseases

Prime Testosterone Support

Clinical evaluation of the spermatogenic activity of the root extract of Ashwagandha in oligospermic males: a pilot study | Hindawi Publishing Corporation

Efficacy and safety of a full-spectrum root extract of Ashwagandha in improving cardiorespiratory endurance in healthy athletic adults | KSM-66® endurance study

Effects of vitamin D supplementation on testosterone levels in men

Association between plasma 25-OH vitamin D and testosterone levels in men | Clinical Endocrinology

Zinc status and serum testosterone levels of healthy adults

Randomized, double-masked, placebo-controlled study of the effects of chromium picolinate supplementation on body composition: a replication and extension | Current Therapeutic Research

Effects of chromium picolinate supplementation on body composition: a randomized, double-masked, placebo-controlled study | Current Therapeutic Research

Targeting optimal nutrient absorption | Sabinsa Corporation — BioPerine®

Sleep - Melatonin Free

Adaptogenic and anxiolytic effects of Ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study

A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults

Efficacy and safety of Ashwagandha root extract in insomnia and anxiety: a double-blind, randomized, placebo-controlled study

Clinical evaluation of the pharmacological impact of Ashwagandha root extract on sleep in healthy volunteers and insomnia patients

Prime Prostate Support

Cranberry fruit powder (Flowens™) improves lower urinary tract symptoms in men: a double-blind, randomized, placebo-controlled study

Nitric oxide-based influence of nitrates on micturition in patients with benign prostatic hyperplasia

A double-blind, placebo-controlled, randomized, longitudinal study on the effects of a plant-based dietary supplement on nitric oxide and mitochondrial metabolic activity

Oxidative stress or redox signalling — new insights into the effects of a proprietary multifunctional botanical dietary supplement

Systemic nitric oxide augmentation leads to a rapid decrease of the bladder outlet resistance in healthy men

Liver & Kidney

Pharmacological studies of artichoke leaf extract and their health benefits

Globe artichoke: a functional food and source of nutraceutical ingredients

Cranberry — health professional overview

Artichoke leaf extract reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial

Biosafety, antioxidant status, and metabolites in urine after consumption of dried cranberry juice in healthy women: a pilot double-blind placebo-controlled trial

Dosage effect on uropathogenic E. coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content

Cranberry fruit powder (Flowens™) improves lower urinary tract symptoms in men: a double-blind, randomized placebo-controlled study

Efficacy of daily intake of dried cranberry 500 mg in women with overactive bladder: a randomized, double-blind, placebo-controlled study

Cranberry proanthocyanidins and the maintenance of urinary tract health

Hormone Balance for Women

Efficacy and safety of Shatavari root extract for perimenopause: randomized, double-blind, placebo-controlled study

Efficacy and safety of Shatavari root extract for menopausal symptoms: a randomized, double-blind, three-arm, placebo-controlled study

Vitamin D and reproductive hormones across the menstrual cycle

Treatment for premenstrual syndrome with Vitex agnus castus: a prospective, randomized, multi-center placebo controlled study in China

Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study

Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus

Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women

Adaptogenic and anxiolytic effects of Ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study

Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women

Randomized, double-blind, placebo-controlled study of oral lactobacilli to improve the vaginal flora of postmenopausal women

Beyond NAD+

†he effects of a multi-ingredient supplement containing Wasabia japonica extract, theacrine, and copper (I) niacin chelate on PBMC DNA methylation, transcriptomics, and sirtuin activity

The effect of short-term NAD3® supplementation on circulating adult stem cells in healthy individuals aged 40–70 years

A nonrandomized study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects

Yüth™ polyamines: a new take on healthy aging

Riboflavin fact sheet for health professionals

Enhance trial: effects of NAD3® on hallmarks of aging and clinical endpoints of health in middle aged adults

Vitamin B12 fact sheet for health professionals

B vitamins and the brain: mechanisms, dose and efficacy — a review

We build products we would take ourselves.